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Syngeneic Mouse Tumor Model
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Over 30 validated syngeneic models for immune profiles in spleen, tumor and blood, with rapid expanding model panel
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Efficacy studies including immune check point inhibitors
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Anti-PD-1 response was well validated in these models
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Highly response Model : MC38, Renca
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Medium response : CT26, EMT6, MB49
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Low response : LL2, TC1, B16F10, 4T1
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Treatment associated TIL (Tumor Infiltrate Lymphocyte) profiling by FACS analysis
Partial list of validated syngenieic mouse tumor models:
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